Gpam^em1Hzhu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpam^em1Hzhu
• Name: glycerol-3-phosphate acyltransferase, mitochondrial; endonuclease-mediated mutation 1, Hao Zhu
• MGI ID: MGI:7494178
• Synonyms: Gpam^f
• Gene: Gpam Location: Chr19:55056067-55115666 bp, - strand Genetic Position: Chr19, 50.81 cM
• Alliance: Gpam^em1Hzhu page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 genome editing technology was used to insert loxP sites flanking exon 3. (J:337236)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpam Mutation: 50 strains or lines available

References

• Original: J:337236 Wang Z, et al., Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease. Cell. 2023 Apr 27;186(9):1968-1984.e20
• All: 1 reference(s)