Got1^em1Sjm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Got1^em1Sjm
• Name: glutamic-oxaloacetic transaminase 1, soluble; endonuclease-mediated mutation 1, Sean J Morrison
• MGI ID: MGI:7494112
• Synonyms: Got1^fl
• Gene: Got1 Location: Chr19:43488191-43513044 bp, - strand Genetic Position: Chr19, 36.67 cM
• Alliance: Got1^em1Sjm page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 genome editing technology was used to insert loxP sites flanking exon 3. (J:337216)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Got1 Mutation: 47 strains or lines available

References

• Original: J:337216 Qi L, et al., Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration. Cell Stem Cell. 2021 Nov 4;28(11):1982-1999.e8
• All: 1 reference(s)