Ifnl2^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Ifnl2^tm1.1Arte
• Name: interferon lambda 2; targeted mutation 1.1, Taconic Artemis
• MGI ID: MGI:7493919
• Synonyms: Ifnl2^Egfp
• Gene: Ifnl2 Location: Chr7:28208261-28209880 bp, - strand Genetic Position: Chr7, 16.8 cM
• Alliance: Ifnl2^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:258140
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (No functional change, Reporter)
• Mutation: Insertion
• Mutation details: A T2A-Egfp coding sequence was inserted in between the last coding codon and the STOP codon in exon 5, keeping the reporter in translation frame. An adjacent frt-flanked puromycin selection cassette was removed via FLP-mediated recombination. (J:258140)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ifnl2 Mutation: 12 strains or lines available

References

• Original: J:258140 Galani IE, et al., Interferon-lambda Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness. Immunity. 2017 May 16;46(5):875-890.e6
• All: 2 reference(s)