Hc^em1Hasty
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hc^em1Hasty
• Name: hemolytic complement; endonuclease-mediated mutation 1, Alyssa Hasty
• MGI ID: MGI:7493589
• Gene: Hc Location: Chr2:34873343-34951450 bp, - strand Genetic Position: Chr2, 23.22 cM, cytoband cen-C1
• Alliance: Hc^em1Hasty page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 3 deleted 568 bp. (J:341386)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hc Mutation: 123 strains or lines available

References

• Original: J:341386 Winn NC, et al., Deletion of complement factor 5 amplifies glucose intolerance in obese male but not female mice. Am J Physiol Endocrinol Metab. 2023 Oct 1;325(4):E325-E335
• All: 1 reference(s)