Evi2b^tm1Ciphe
Targeted Allele Detail

Summary

• Symbol: Evi2b^tm1Ciphe
• Name: ecotropic viral integration site 2b; targeted mutation 1, Centre d'ImmunoPhenomique
• MGI ID: MGI:7491920
• Gene: Evi2b Location: Chr11:79405882-79414588 bp, - strand Genetic Position: Chr11, 46.8 cM
• Alliance: Evi2b^tm1Ciphe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:261305
• Parent Cell Line: JM8.F6 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• Excision of full coding sequence. Exon 2 was replaced with a loxP site. (J:261305)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Evi2b Mutation: 9 strains or lines available

References

• Original: J:261305 Zjablovskaja P, et al., EVI2B is a C/EBPalpha target gene required for granulocytic differentiation and functionality of hematopoietic progenitors. Cell Death Differ. 2017 Apr;24(4):705-716
• All: 1 reference(s)