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Tg(Gm5127-cre/ERT2)1Mhsi
Transgene Detail
Summary
Symbol: Tg(Gm5127-cre/ERT2)1Mhsi
Name: transgene insertion 1, Michael Simons
MGI ID: MGI:7490280
Synonyms: Gm5127(BAC)CreERT2
Transgene: Tg(Gm5127-cre/ERT2)1Mhsi  Location: unknown  
Alliance: Tg(Gm5127-cre/ERT2)1Mhsi page
Transgene
origin
Strain of Origin:  (C57BL/6J x SJL/J)F2
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Gm5127-cre/ERT2)1Mhsi expression driven by 1 gene
 
Mutation detailsThe bacterial artificial chromosome, RP23-113I19, containing the Gm5127 predicted gene (including 27 kb of 5' upstream and 70 kb of 3' downstream) was modified by recombineering to insert an inducible cre recombinase/ERT2 cassette (pCAG-CreERT2) and a FRT flanked neomycin cassette (with 50 bp overhangs) into the start codon of the Gm5127 gene sequence. (J:336605)
Recombinase
activity
Activity:
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Driver: Gm5127 (mouse)
Summary of all recombinase alleles driven by Gm5127.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:336605 Lee HW, et al., Role of Venous Endothelial Cells in Developmental and Pathologic Angiogenesis. Circulation. 2021 Oct 19;144(16):1308-1322
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory