P2rx4^em1Rmur
Endonuclease-mediated Allele Detail

Summary

• Symbol: P2rx4^em1Rmur
• Name: purinergic receptor P2X, ligand-gated ion channel 4; endonuclease-mediated mutation 1, Rieko Muramatsu
• MGI ID: MGI:7490196
• Gene: P2rx4 Location: Chr5:122845607-122867801 bp, + strand Genetic Position: Chr5, 62.53 cM
• Alliance: P2rx4^em1Rmur page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 2. (J:259935)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any P2rx4 Mutation: 29 strains or lines available

References

• Original: J:259935 Ozaki T, et al., The P2X4 receptor is required for neuroprotection via ischemic preconditioning. Sci Rep. 2016 May 13;6:25893
• All: 2 reference(s)