Bmal1^em2Yshtn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bmal1^em2Yshtn
• Name: basic helix-loop-helix ARNT like 1; endonuclease-mediated mutation 2, Hikari Yoshitane
• MGI ID: MGI:7490188
• Synonyms: Bmal1-DRRE mouse #2
• Gene: Bmal1 Location: Chr7:112806672-112913333 bp, + strand Genetic Position: Chr7, 59.17 cM, cytoband F2-F3
• Alliance: Bmal1^em2Yshtn page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Intragenic deletion
• CRISPR-targeted deleted 41 bp including the RRE domain. (J:336593)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmal1 Mutation: 137 strains or lines available

References

• Original: J:336593 Abe YO, et al., Rhythmic transcription of Bmal1 stabilizes the circadian timekeeping system in mammals. Nat Commun. 2022 Aug 23;13(1):4652
• All: 1 reference(s)