Shox2^{em1(cre)Zyliu}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Shox2^{em1(cre)Zyliu}
• Name: SHOX homeobox 2; endonuclease-mediated mutation 1, Zhiyong Liu
• MGI ID: MGI:7489962
• Synonyms: Shox2-3*V5-P2A-Cre, Shox2*V5-Cre
• Gene: Shox2 Location: Chr3:66879060-66889104 bp, - strand Genetic Position: Chr3, 30.76 cM, cytoband E3-F1
• Alliance: Shox2^{em1(cre)Zyliu} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag, Recombinase)
• Mutation: Insertion
• Shox2^{em1(cre)Zyliu} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Shox2 (MGI:1201673)

• Mutation details: Using CRISPR/Cas9 technology, 3*V5-P2A-Cre was inserted into the Shox2 locus in which three V5 tags are fused at the C terminus of the gene. (J:324832)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Shox2 (mouse) Summary of all recombinase alleles driven by Shox2. Comparative matrix view of recombinase activities Alliance mouse Shox2 gene page

Expression

In Mice Carrying this Mutation:

13 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Shox2 Mutation: 19 strains or lines available

References

• Original: J:324832 Sun Y, et al., Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages. Cell Rep. 2022 Mar 22;38(12):110542
• All: 1 reference(s)