Rsph6a^em3Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rsph6a^em3Osb
• Name: radial spoke head 6 homolog A (Chlamydomonas); endonuclease-mediated mutation 3, Osaka University
• MGI ID: MGI:7489904
• Gene: Rsph6a Location: Chr7:18788615-18808372 bp, + strand Genetic Position: Chr7, 9.46 cM, cytoband A2
• Alliance: Rsph6a^em3Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR-targeting introduced the mutations responsible for the amino acid substitutions of serine with alanine at positions 17 and 20 (S17A, S20A) . (J:301453)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Rsph6a Mutation: 36 strains or lines available

References

• Original: J:301453 Miyata H, et al., CRISPR/CAS9-mediated amino acid substitution reveals phosphorylation residues of RSPH6A are not essential for male fertility in mice. Biol Reprod. 2020 Oct 29;103(5):912-914
• All: 1 reference(s)