Ebf3^tm1.1Asf
Targeted Allele Detail

Summary

• Symbol: Ebf3^tm1.1Asf
• Name: early B cell factor 3; targeted mutation 1.1, Atsuko Sehara-Fujisawa
• MGI ID: MGI:7489747
• Synonyms: Ebf3^flox
• Gene: Ebf3 Location: Chr7:136795402-136916174 bp, - strand Genetic Position: Chr7, 82.26 cM, cytoband F3-F4
• Alliance: Ebf3^tm1.1Asf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:288306
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites as well as an FRT-flanked neomycin resistance cassette were inserted to flank exons 5 and 6. The FRT-flanked neomycin resistance cassette was removed via FLP-mediated recombination in the germline. (J:288306)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ebf3 Mutation: 37 strains or lines available

References

• Original: J:288306 Kuriki M, et al., Transient and lineage-restricted requirement of Ebf3 for sternum ossification. Development. 2020 May 12;147(9):dev186239
• All: 1 reference(s)