L2hgdh^{Tn(pb-Act-RFP)1Klg}
Transposon induced Allele Detail

Summary

• Symbol: L2hgdh^{Tn(pb-Act-RFP)1Klg}
• Name: L-2-hydroxyglutarate dehydrogenase; transposon insertion 1, Kun-Liang Guan
• MGI ID: MGI:7489683
• Gene: L2hgdh Location: Chr12:69737210-69771648 bp, - strand Genetic Position: Chr12, 28.94 cM
• Alliance: L2hgdh^{Tn(pb-Act-RFP)1Klg} page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Transposon induced (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A modified piggyBac transposon harboring the red fluorescent protein (RFP) gene was inserted between exon 1 and exon 2 of the gene. (J:243936)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any L2hgdh Mutation: 17 strains or lines available

References

• Original: J:243936 Ma S, et al., L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration. Mol Cell Biol. 2017 Apr 15;37(8)
• All: 1 reference(s)