Il22^tm2Flv
Targeted Allele Detail

Summary

• Symbol: Il22^tm2Flv
• Name: interleukin 22; targeted mutation 2, Richard A Flavell
• MGI ID: MGI:7488470
• Synonyms: IL-22 BFP, IL-22^sgBFP
• Gene: Il22 Location: Chr10:118040847-118045952 bp, + strand Genetic Position: Chr10, 66.67 cM
• Alliance: Il22^tm2Flv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:292263
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An internal ribosomal entry site (IRES)-BFP reporter was integrated into the 3 untranslated region (UTR) of the gene. (J:292263)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il22 Mutation: 29 strains or lines available

References

• Original: J:292263 Perez LG, et al., TGF-beta signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer. Nat Commun. 2020 May 25;11(1):2608
• All: 3 reference(s)