Gata3^tm1.1Mpu
Targeted Allele Detail

Summary

• Symbol: Gata3^tm1.1Mpu
• Name: GATA binding protein 3; targeted mutation 1.1, Takashi Moriguchi
• MGI ID: MGI:7488142
• Synonyms: Gata3^g, Gata3^{tm1.1(GFP)Mpu}
• Gene: Gata3 Location: Chr2:9861889-9894845 bp, - strand Genetic Position: Chr2, 6.69 cM
• Alliance: Gata3^tm1.1Mpu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:236172
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a cDNA encoding a GATA3-GFP fusion protein in frame at the start codon. Cre-mediated recombination removed the selection cassette. (J:236172)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata3 Mutation: 31 strains or lines available

References

• Original: J:236172 Moriguchi T, et al., Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect. Mol Cell Biol. 2016 Sep 1;36(17):2272-81
• All: 1 reference(s)