Gad1^{tm1(tetO)Ksak}
Targeted Allele Detail

Summary

• Symbol: Gad1^{tm1(tetO)Ksak}
• Name: glutamate decarboxylase 1; targeted mutation 1, Kenji Sakimura
• MGI ID: MGI:7486731
• Synonyms: Gad1^STOP-TetO
• Gene: Gad1 Location: Chr2:70392109-70432358 bp, + strand Genetic Position: Chr2, 41.63 cM, cytoband D
• Alliance: Gad1^{tm1(tetO)Ksak} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:303860
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Modified regulatory region)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a floxed stop cassette followed by tetO the endogenous promoter and coding sequence. (J:303860)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gad1 Mutation: 64 strains or lines available

References

• Original: J:303860 Miyata S, et al., Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice. Mol Brain. 2021 Jan 7;14(1):5
• All: 1 reference(s)