Hlfem2(cre/ERT2)Suda
Endonuclease-mediated Allele Detail
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Symbol: |
Hlfem2(cre/ERT2)Suda |
Name: |
hepatic leukemia factor; endonuclease-mediated mutation 2, Toshio Suda |
MGI ID: |
MGI:7486479 |
Synonyms: |
Hlf-CreERT2 |
Gene: |
Hlf Location: Chr11:90227362-90281721 bp, - strand Genetic Position: Chr11, 55.03 cM
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Alliance: |
Hlfem2(cre/ERT2)Suda page
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Allele Type: |
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Endonuclease-mediated (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Hlfem2(cre/ERT2)Suda expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Hlf (MGI:96108) |
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Mutation details: Using the CRISPR/Cas9 method, a T2A-CreERT2 fusion gene was inserted before the endogenous stop codon within exon 4.
(J:328986, J:336140)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Hlf
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Hlf Mutation: |
15 strains or lines available
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Original: |
J:336140 Yokomizo T, et al., Independent origins of fetal liver haematopoietic stem and progenitor cells. Nature. 2022 Sep;609(7928):779-784 |
All: |
2 reference(s) |
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