Tfeb^em1Xpy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tfeb^em1Xpy
• Name: transcription factor EB; endonuclease-mediated mutation 1, Xiang-Ping Yang
• MGI ID: MGI:7486081
• Synonyms: Tcfeb^fl
• Gene: Tfeb Location: Chr17:48047962-48103341 bp, + strand Genetic Position: Chr17, 23.99 cM, cytoband D
• Alliance: Tfeb^em1Xpy page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exons 5-7 were flanked by loxP sites via CRISPR/Cas9 technology. (J:336031)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tfeb Mutation: 49 strains or lines available

References

• Original: J:336031 Xia M, et al., Transcription factor EB coordinates environmental cues to regulate T regulatory cells' mitochondrial fitness and function. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2205469119
• All: 1 reference(s)