Dusp5^tm2Skey
Targeted Allele Detail

Summary

• Symbol: Dusp5^tm2Skey
• Name: dual specificity phosphatase 5; targeted mutation 2, Stephen M Keyse
• MGI ID: MGI:7485837
• Synonyms: Dusp5M^fl
• Gene: Dusp5 Location: Chr19:53517576-53530240 bp, + strand Genetic Position: Chr19, 47.98 cM
• Alliance: Dusp5^tm2Skey page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:324774
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 1 was flanked by loxP sites. (J:324774)

Tumor Data

List all tumor models in MMHCdb carrying Dusp5^tm2Skey

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dusp5 Mutation: 17 strains or lines available

References

• Original: J:324774 Kidger AM, et al., Suppression of mutant Kirsten-RAS (KRAS(G12D))-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6. Oncogene. 2022 May;41(20):2811-2823
• All: 1 reference(s)