Ly6atm1.1(cre/ERT2)Geno
Targeted Allele Detail
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Symbol: |
Ly6atm1.1(cre/ERT2)Geno |
Name: |
lymphocyte antigen 6 family member A; targeted mutation 1.1, Genoway |
MGI ID: |
MGI:7484560 |
Synonyms: |
Sca-1-CreERT2, Sca-1(Ly6a)-CreERT2 |
Gene: |
Ly6a Location: Chr15:74866726-74869880 bp, - strand Genetic Position: Chr15, 34.29 cM
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Alliance: |
Ly6atm1.1(cre/ERT2)Geno page
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Germline Transmission: |
Earliest citation of germline transmission:
J:335791
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Ly6atm1.1(cre/ERT2)Geno expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A cDNA encoding CreERT2 coding sequence and frt sites flanked neomycin cassette was inserted in frame of the Ly6a ATG start sequence by homologous recombination in ES cells. The neo selection sequence was later deleted by applying Flp-frt based system.
(J:335791)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Ly6a
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ly6a Mutation: |
20 strains or lines available
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Original: |
J:335791 Ni Z, et al., Multilineage commitment of Sca-1(+) cells in reshaping vein grafts. Theranostics. 2023;13(7):2154-2175 |
All: |
1 reference(s) |
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