Areg^em1Lira
Endonuclease-mediated Allele Detail

Summary

• Symbol: Areg^em1Lira
• Name: amphiregulin; endonuclease-mediated mutation 1, Sergio A Lira
• MGI ID: MGI:7481313
• Synonyms: Areg^fl
• Gene: Areg Location: Chr5:91287458-91296291 bp, + strand Genetic Position: Chr5, 44.78 cM
• Alliance: Areg^em1Lira page

Mutation origin

• Strain of Origin: B6D2F1

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: Utilizing CRISPRCas9n technology, loxP sequences were inserted into intron 2 and intron 4, flanking exon 3 and exon 4 of the Areg gene. (J:334817)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Areg Mutation: 33 strains or lines available

References

• Original: J:334817 Tsou AM, et al., Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces. Nature. 2022 Nov;611(7937):787-793
• All: 2 reference(s)