Vsig4^em1Zze
Endonuclease-mediated Allele Detail

Summary

• Symbol: Vsig4^em1Zze
• Name: V-set and immunoglobulin domain containing 4; endonuclease-mediated mutation 1, Zhutian Zeng
• MGI ID: MGI:7471134
• Synonyms: Crig^-
• Gene: Vsig4 Location: ChrX:95290809-95337044 bp, - strand Genetic Position: ChrX, 42.69 cM
• Alliance: Vsig4^em1Zze page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology was used to delete exons 1 and 2. (J:335481)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vsig4 Mutation: 11 strains or lines available

References

• Original: J:335481 Liu W, et al., In situ expansion and reprogramming of Kupffer cells elicit potent tumoricidal immunity against liver metastasis. J Clin Invest. 2023 Apr 17;133(8)
• All: 1 reference(s)