Gt(ROSA)26Sor^{tm1(CAG-Tlx1)Rygo}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-Tlx1)Rygo}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ryo Goitsuka
• MGI ID: MGI:7470934
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-Tlx1)Rygo} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278071
• Parent Cell Line: IDG3.2 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The targeting construct inserted the CAG promoter driving ubiquitous expression of an HA-tagged mouse gene. A floxed stop cassette prevents expression until cre-mediated recombination. (J:278071)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1060 strains or lines available

References

• Original: J:278071 Oda A, et al., Niche-induced extramedullary hematopoiesis in the spleen is regulated by the transcription factor Tlx1. Sci Rep. 2018 May 29;8(1):8308
• All: 1 reference(s)