Tg(Clgn-Nicol1)2Osb
Transgene Detail

Summary

• Symbol: Tg(Clgn-Nicol1)2Osb
• Name: transgene insertion 2, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:7470871
• Synonyms: Clgn-Nicol, Tg(Clgn-Gm1673/PA/1D4)2Osb
• Transgene: Tg(Clgn-Nicol1)2Osb Location: unknown
• Alliance: Tg(Clgn-Nicol1)2Osb page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA/2J)F1

Transgene description

• Transgene Type: Transgenic (Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Clgn-Nicol1)2Osb expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Nicol1 (MGI:2686519)

• Tg(Clgn-Nicol1)2Osb expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Clgn (MGI:107472)

• Mutation details: The mouse promoter drives sperm-specific expression of the mouse sequence with an Rho1D4 epitope. Line 2 was generated. (J:335479)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:335479 Kiyozumi D, et al., A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility. Nat Commun. 2023 Apr 24;14(1):2354
• All: 1 reference(s)