Carmn^tm1.1Cya
Targeted Allele Detail

Summary

• Symbol: Carmn^tm1.1Cya
• Name: cardiac mesoderm enhancer-associated non-coding RNA; targeted mutation 1.1, Cyagen Biosciences
• MGI ID: MGI:7470774
• Synonyms: Carmn^PFG
• Gene: Carmn Location: Chr18:61782696-61798608 bp, - strand Genetic Position: Chr18, 34.64 cM
• Alliance: Carmn^tm1.1Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:319356
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted into intron 2 an inverted splice acceptor-membrane bound GFP cassette flanked by two pairs of loxP and lox2272 sites in opposite orientation. A loxP site was inserted upstream of exon 2. Dre-mediated recombination removed the Rox flanked neomycin resistance cassette. (J:319356)

Expression

In Mice Carrying this Mutation:

89 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Carmn Mutation: 1 strain or line available

References

• Original: J:319356 Dong K, et al., CARMN Is an Evolutionarily Conserved Smooth Muscle Cell-Specific LncRNA That Maintains Contractile Phenotype by Binding Myocardin. Circulation. 2021 Dec 7;144(23):1856-1875
• All: 2 reference(s)