Fndc5^tm1Brsp
Targeted Allele Detail

Summary

• Symbol: Fndc5^tm1Brsp
• Name: fibronectin type III domain containing 5; targeted mutation 1, Bruce M Spiegelman
• MGI ID: MGI:7470749
• Synonyms: Fndc5^fl
• Gene: Fndc5 Location: Chr4:129030672-129038386 bp, + strand Genetic Position: Chr4, 62.93 cM
• Alliance: Fndc5^tm1Brsp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:335307
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exons 3 and 4 were flanked by loxP sites. (J:335307)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fndc5 Mutation: 21 strains or lines available

References

• Original: J:335307 Islam MR, et al., Exercise hormone irisin is a critical regulator of cognitive function. Nat Metab. 2021 Aug;3(8):1058-1070
• All: 1 reference(s)