Tg(Tcra-Trav14-1/Traj42)1Reddy
Transgene Detail

Summary

• Symbol: Tg(Tcra-Trav14-1/Traj42)1Reddy
• Name: transgene insertion 1, Jay Reddy
• MGI ID: MGI:7469497
• Synonyms: Tg(Tcra-Trav14-1/Traj42)1Reddy Tg(Tcrb-Trbv2/Trbd1/Trbj2-5)2Reddy
• Transgene: Tg(Tcra-Trav14-1/Traj42)1Reddy Location: unknown
• Alliance: Tg(Tcra-Trav14-1/Traj42)1Reddy page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: Randomly inserted TCR alpha transgene construct that combines rearranged genomic DNA of Trav14-1*02 and Traj42*01. Cardiac myosin heavy chain alpha 334-352-specific T cell receptor transgenic mice express only the alpha chain. (J:349822)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available

References

• Original: J:349822 Sur M, et al., Transgenic Mice Expressing Functional TCRs Specific to Cardiac Myhc-alpha 334-352 on Both CD4 and CD8 T Cells Are Resistant to the Development of Myocarditis on C57BL/6 Genetic Background. Cells. 2023 Sep 25;12(19)
• All: 2 reference(s)