Mcoln3tm1.1(cre)Lrcb
Targeted Allele Detail
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Symbol: |
Mcoln3tm1.1(cre)Lrcb |
Name: |
mucolipin 3; targeted mutation 1.1, Christian Grimm |
MGI ID: |
MGI:7469457 |
Synonyms: |
Trpml3IRES-Cre |
Gene: |
Mcoln3 Location: Chr3:145823205-145847561 bp, + strand Genetic Position: Chr3, 71.03 cM
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Alliance: |
Mcoln3tm1.1(cre)Lrcb page
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Germline Transmission: |
Earliest citation of germline transmission:
J:320955
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Mcoln3tm1.1(cre)Lrcb expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The IRES-Cre-PGK-Neomycin cassette was inserted at 5 bp after the stop codon in exon 12 of the Mcoln3 (Trpml3) gene. The resulting mice were crossed with FLP deleter mice to remove the neo cassette.
(J:320955)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Mcoln3
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mcoln3 Mutation: |
35 strains or lines available
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Original: |
J:320955 Spix B, et al., Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice. Nat Commun. 2022 Jan 14;13(1):318 |
All: |
1 reference(s) |
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