Tg(Vav1-HBEGF,-GFP)1Cfors
Transgene Detail

Summary

• Symbol: Tg(Vav1-HBEGF,-GFP)1Cfors
• Name: transgene insertion 1, Camilla Forsberg
• MGI ID: MGI:7464989
• Synonyms: Vav-DTR
• Transgene: Tg(Vav1-HBEGF,-GFP)1Cfors Location: unknown
• Alliance: Tg(Vav1-HBEGF,-GFP)1Cfors page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Vav1-HBEGF,-GFP)1Cfors expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  monkey	HBEGF

• Mutation details: The mouse Vav1 promoter drives expression of a loxP-flanked diptheria toxin receptor (DTR, HBGEF) and stop codon, a second loxP and a GFP gene. GFP is not expressed unless Cre-mediated recombination of the loxP sites occurs. (J:321689)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:321689 Rodriguez Y Baena A, et al., New transgenic mouse models enabling pan-hematopoietic or selective hematopoietic stem cell depletion in vivo. Sci Rep. 2022 Feb 24;12(1):3156
• All: 1 reference(s)