Epor^{em1(cre)Bcgen}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Epor^{em1(cre)Bcgen}
• Name: erythropoietin receptor; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7464882
• Synonyms: EpoR-tdTomato-Cre
• Gene: Epor Location: Chr9:21870193-21874802 bp, - strand Genetic Position: Chr9, 7.93 cM
• Alliance: Epor^{em1(cre)Bcgen} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase, Reporter)
• Mutation: Insertion
• Epor^{em1(cre)Bcgen} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Epor (MGI:95408)

• Mutation details: Using CRISPR/Cas9 technology, P2A-tdTomato-P2A-iCre cassette was inserted into the C-terminus just before the stop codon in the exon 8 of the Epor gene. (J:315468)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Epor (mouse) Summary of all recombinase alleles driven by Epor. Comparative matrix view of recombinase activities Alliance mouse Epor gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epor Mutation: 25 strains or lines available

References

• Original: J:315468 Zhang H, et al., EpoR-tdTomato-Cre mice enable identification of EpoR expression in subsets of tissue macrophages and hematopoietic cells. Blood. 2021 Nov 18;138(20):1986-1997
• All: 1 reference(s)