Npfftm1.1(icre)Xen
Targeted Allele Detail
|
Symbol: |
Npfftm1.1(icre)Xen |
Name: |
neuropeptide FF-amide peptide precursor; targeted mutation 1.1, Taconic Biosciences |
MGI ID: |
MGI:7464745 |
Synonyms: |
NPFFCre |
Gene: |
Npff Location: Chr15:102432274-102433056 bp, - strand Genetic Position: Chr15, 57.65 cM, cytoband F3
|
Alliance: |
Npfftm1.1(icre)Xen page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:334879
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
Not Specified
|
|
Allele Type: |
|
Targeted (Recombinase) |
Mutation: |
|
Insertion
|
|
|
Npfftm1.1(icre)Xen expression driven by
1 gene
Knock-in expression driven by:
|
|
|
Mutation details: Using a conventional ES cell targeting strategy and homologous recombination, the T2A peptide and the open reading frame of improved Cre recombinase (iCre) were inserted between the last amino acid and the translation termination codon in exon 3 of the Npff gene. A positive selection marker (Puromycin resistance) flanked by FRT sites was removed by crossing with germline Flpe mice.
(J:334879)
|
|
|
Activity: |
Tissue activity of this recombinase allele
|
Driver:
|
Npff
(mouse)
|
|
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Npff Mutation: |
6 strains or lines available
|
|
Original: |
J:334879 Quillet R, et al., Characterisation of NPFF-expressing neurons in the superficial dorsal horn of the mouse spinal cord. Sci Rep. 2023 Apr 11;13(1):5891 |
All: |
1 reference(s) |
|