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Endonuclease-mediated Allele Detail
Symbol: Map10em1(IMPC)J
Name: microtubule-associated protein 10; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:7463972
Gene: Map10  Location: Chr8:126396557-126400098 bp, + strand  Genetic Position: Chr8, 73.65 cM, cytoband E2
Alliance: Map10em1(IMPC)J page
IMPC: Map10 gene page
Strain of Origin:  C57BL/6NJ
Project Collection: IMPC
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThis allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCAATGGCGACCACGGCGGC and GCAGATGTCTTTGCACTGTC, which resulted in a 2611 bp deletion beginning at Chromosome 8 position 125,669,882 bp and ending after 125,672,492 bp (GRCm38/mm10). This mutation deletes 2611 bp of ENSMUSE00000346397 (exon 1) and is predicted to cause a change of amino acid sequence after residue 5 and early truncation 5 amino acids later. (J:188991)
Inheritance:    Not Specified
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Map10 Mutation:  14 strains or lines available
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory