Ptbp1^em2Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ptbp1^em2Gpt
• Name: polypyrimidine tract binding protein 1; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
• MGI ID: MGI:7463970
• Synonyms: Ptbp1^fl
• Gene: Ptbp1 Location: Chr10:79690502-79700269 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Ptbp1^em2Gpt page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exon 2 was flanked by loxP sites using CRISPR/Cas9 technology. (J:334567)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptbp1 Mutation: 36 strains or lines available

References

• Original: J:334567 Liu H, et al., Endothelial deletion of PTBP1 disrupts ventricular chamber development. Nat Commun. 2023 Mar 31;14(1):1796
• All: 1 reference(s)