Aldh7a1^em1Syki
Endonuclease-mediated Allele Detail

Summary

• Symbol: Aldh7a1^em1Syki
• Name: aldehyde dehydrogenase family 7, member A1; endonuclease-mediated mutation 1, Soo-Youl Kim
• MGI ID: MGI:7462673
• Gene: Aldh7a1 Location: Chr18:56657794-56706112 bp, - strand Genetic Position: Chr18, 30.55 cM
• Alliance: Aldh7a1^em1Syki page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-cas9 mediated recombination created a 38 bp deletion in exon 5. (J:308811)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aldh7a1 Mutation: 43 strains or lines available

References

• Original: J:308811 Lee JS, et al., Overall survival of pancreatic ductal adenocarcinoma is doubled by Aldh7a1 deletion in the KPC mouse. Theranostics. 2021;11(7):3472-3488
• All: 1 reference(s)