Hmgb2^em1Mode
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hmgb2^em1Mode
• Name: high mobility group box 2; endonuclease-mediated mutation 1, Delin Mo
• MGI ID: MGI:7462648
• Gene: Hmgb2 Location: Chr8:57964941-57969033 bp, + strand Genetic Position: Chr8, 29.9 cM
• Alliance: Hmgb2^em1Mode page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-cas9 mediated recombination targeting exons 2-5 created an approximately 4 kb deletion. (J:309141)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hmgb2 Mutation: 10 strains or lines available

References

• Original: J:309141 Fang Y, et al., High mobility group box 2 regulates skeletal muscle development through ribosomal protein S6 kinase 1. FASEB J. 2020 Sep;34(9):12367-12378
• All: 1 reference(s)