Atf6^tm1.1Hota
Targeted Allele Detail

Summary

• Symbol: Atf6^tm1.1Hota
• Name: activating transcription factor 6; targeted mutation 1.1, Gokhan S Hotamisligil
• MGI ID: MGI:7462415
• Gene: Atf6 Location: Chr1:170532243-170695340 bp, - strand Genetic Position: Chr1, 76.96 cM
• Alliance: Atf6^tm1.1Hota page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:334705
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The floxed exons 8 and 9 were removed via cre-mediated recombination. (J:334705)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atf6 Mutation: 48 strains or lines available

References

• Original: J:334705 Yu R, et al., ATF6 deficiency damages the development of spermatogenesis in male Atf6 knockout mice. Andrologia. 2022 Apr;54(3):e14350
• All: 1 reference(s)