Tg(SNCA*A53T)62Gpt
Transgene Detail

Summary

• Symbol: Tg(SNCA*A53T)62Gpt
• Name: transgene insertion 62, GemPharmatech Co., Ltd
• MGI ID: MGI:7462313
• Synonyms: Tg(hSNCA-A53T)62
• Transgene: Tg(SNCA*A53T)62Gpt Location: unknown
• Alliance: Tg(SNCA*A53T)62Gpt page

Transgene origin

• Strain of Origin: C57BL/6JGpt

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(SNCA*A53T)62Gpt expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SNCA (6622)

  Snca	(MGI:1277151)

• Mutation details: The transgene contains the human gene with the amino acid substitution of alanine with threonine at position 53. Line 62 was generated. (J:293217, J:348472)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:348472 Guo C, et al., Plasminogen degrades alpha-synuclein, Tau and TDP-43 and decreases dopaminergic neurodegeneration in mouse models of Parkinson's disease. Sci Rep. 2024 Apr 13;14(1):8581
• All: 2 reference(s)