Tg(HTT*130Q)90Gpt
Transgene Detail

Summary

• Symbol: Tg(HTT*130Q)90Gpt
• Name: transgene insertion 90, GemPharmatech Co., Ltd
• MGI ID: MGI:7462312
• Synonyms: Tg(hHTT-CAG130)90
• Transgene: Tg(HTT*130Q)90Gpt Location: unknown
• Alliance: Tg(HTT*130Q)90Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Tg(HTT*130Q)90Gpt expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  HTT (3064)

  Htt	(MGI:96067)

• The transgene contains the human gene with 130 glutamine tract. Line 90 was generated. (J:293217, J:368085)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:368085 Sun H, et al., Gastrodin Improves the Activity of the Ubiquitin-Proteasome System and the Autophagy-Lysosome Pathway to Degrade Mutant Huntingtin. Int J Mol Sci. 2024 Jul 14;25(14)
• All: 2 reference(s)