Dand5^em2Hmd
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dand5^em2Hmd
• Name: DAN domain family member 5, BMP antagonist; endonuclease-mediated mutation 2, Hiroshi Hamada
• MGI ID: MGI:7461790
• Synonyms: Dand5^delta200prox #2
• Gene: Dand5 Location: Chr8:85542034-85558894 bp, - strand Genetic Position: Chr8, 41.17 cM
• Alliance: Dand5^em2Hmd page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 200 bp from the proximal 3' UTR. (J:307831)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dand5 Mutation: 17 strains or lines available

References

• Original: J:307831 Minegishi K, et al., Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex. Nat Commun. 2021 Jul 1;12(1):4071
• All: 1 reference(s)