Pkd2^em1Bky
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pkd2^em1Bky
• Name: polycystin 2, transient receptor potential cation channel; endonuclease-mediated mutation 1, Bradley K Yoder
• MGI ID: MGI:7461532
• Synonyms: Pkd2^{exon 15 Halo}
• Gene: Pkd2 Location: Chr5:104607316-104653685 bp, + strand Genetic Position: Chr5, 50.68 cM
• Alliance: Pkd2^em1Bky page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR-targeting replaced the STOP codon with the coding region of the HaloTag protein resulting in expression of a fusion protein from the endogenous locus. (J:334619)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pkd2 Mutation: 85 strains or lines available

References

• Original: J:334619 Haycraft CJ, et al., Direct Data Submission for a Pkd2 Allele. MGI Direct Data Submission. 2023
• All: 1 reference(s)