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Adam18tm2Osb
Targeted Allele Detail
Summary
Symbol: Adam18tm2Osb
Name: a disintegrin and metallopeptidase domain 18; targeted mutation 2, Research Institute for Microbial Diseases, Osaka University
MGI ID: MGI:7451035
Gene: Adam18  Location: Chr8:25092262-25164771 bp, - strand  Genetic Position: Chr8, 12.82 cM, cytoband A3
Alliance: Adam18tm2Osb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:234235
Parent Cell Line:  EGR-G101 (ES Cell)
Strain of Origin:  C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
    The targeting construct generated a null allele. (J:234235)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adam18 Mutation:  75 strains or lines available
References
Original:  J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory