Wdr5^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Wdr5^em1Gpt
• Name: WD repeat domain 5; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7451004
• Synonyms: Wdr5^fl
• Gene: Wdr5 Location: Chr2:27405169-27426547 bp, + strand Genetic Position: Chr2, 19.38 cM
• Alliance: Wdr5^em1Gpt page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 technology inserted loxP sites flanking exons 3 to 8. (J:334487)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdr5 Mutation: 31 strains or lines available

References

• Original: J:334487 Liu L, et al., Loss of Wdr5 attenuates MLL-rearranged leukemogenesis by suppressing Myc targets. Biochim Biophys Acta Mol Basis Dis. 2022 Nov 17;1869(2):166600
• All: 1 reference(s)