Atf3^{em1(cre/ERT2)Wlf}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atf3^{em1(cre/ERT2)Wlf}
• Name: activating transcription factor 3; endonuclease-mediated mutation 1, Clifford J Woolf
• MGI ID: MGI:7450981
• Synonyms: Atf3-CreER^T2
• Gene: Atf3 Location: Chr1:190902493-190915530 bp, - strand Genetic Position: Chr1, 96.28 cM, cytoband H6
• Alliance: Atf3^{em1(cre/ERT2)Wlf} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Mutation: Insertion
• Atf3^{em1(cre/ERT2)Wlf} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Atf3 (MGI:109384)

• Using CRISPR/Cas9 technology, the IRES_CreERT2_pA cassette was inserted into the Arf3 locus. (J:329557)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Atf3 (mouse) Summary of all recombinase alleles driven by Atf3. Comparative matrix view of recombinase activities Alliance mouse Atf3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atf3 Mutation: 19 strains or lines available

References

• Original: J:329557 Renthal W, et al., Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury. Neuron. 2020 Oct 14;108(1):128-144.e9
• All: 1 reference(s)