Msi1^{em1(cre/ERT2)Nju}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Msi1^{em1(cre/ERT2)Nju}
• Name: musashi RNA-binding protein 1; endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:7450823
• Synonyms: Msi1^CreERT2
• Gene: Msi1 Location: Chr5:115567734-115593757 bp, + strand Genetic Position: Chr5, 56.09 cM, cytoband E3-F
• Alliance: Msi1^{em1(cre/ERT2)Nju} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Msi1^{em1(cre/ERT2)Nju} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Msi1 (MGI:107376)

• The P2A-CreERT2 expression cassette was knocked into the Msi1 gene stop codon site. (J:324214)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Msi1 (mouse) Summary of all recombinase alleles driven by Msi1. Comparative matrix view of recombinase activities Alliance mouse Msi1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Msi1 Mutation: 31 strains or lines available

References

• Original: J:324214 Sheng X, et al., Cycling Stem Cells Are Radioresistant and Regenerate the Intestine. Cell Rep. 2020 Jul 28;32(4):107952
• All: 1 reference(s)