Ccr2^{em1(mNeonGreen,cre)Cya}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ccr2^{em1(mNeonGreen,cre)Cya}
• Name: C-C motif chemokine receptor 2; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7448950
• Synonyms: Ccr2-mNeonGreen-Cre
• Gene: Ccr2 Location: Chr9:123901987-123913594 bp, + strand Genetic Position: Chr9, 75.05 cM, cytoband F
• Alliance: Ccr2^{em1(mNeonGreen,cre)Cya} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase, Reporter)
• Mutation: Insertion
• Ccr2^{em1(mNeonGreen,cre)Cya} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ccr2 (MGI:106185)

• Mutation details: P2A-mNeonGreen-T2A-Cre cassette replaced TAA stop codon of the Ccr2 gene by using CRISPR/ Cas9 technology. (J:334311)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ccr2 (mouse) Summary of all recombinase alleles driven by Ccr2. Comparative matrix view of recombinase activities Alliance mouse Ccr2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccr2 Mutation: 40 strains or lines available

References

• Original: J:334311 Zhao M, et al., Maturation and specialization of group 2 innate lymphoid cells through the lung-gut axis. Nat Commun. 2022 Dec 9;13(1):7600
• All: 1 reference(s)