Wdr41^em1Fehu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Wdr41^em1Fehu
• Name: WD repeat domain 41; endonuclease-mediated mutation 1, Fenghua Hu
• MGI ID: MGI:7448529
• Synonyms: wdr41^-
• Gene: Wdr41 Location: Chr13:95112852-95159821 bp, + strand Genetic Position: Chr13, 49.22 cM
• Alliance: Wdr41^em1Fehu page

Mutation origin

• Strain of Origin: (C57BL/6J x FVB/N)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdr41 Mutation: 28 strains or lines available

References

• Original: J:294772 Lan Y, et al., SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis. Autophagy. 2019 May;15(5):871-885
• All: 1 reference(s)