Trp53bp2^em8Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trp53bp2^em8Gpt
• Name: transformation related protein 53 binding protein 2; endonuclease-mediated mutation 8, GemPharmatech Co., Ltd
• MGI ID: MGI:7448505
• Gene: Trp53bp2 Location: Chr1:182236737-182289997 bp, + strand Genetic Position: Chr1, 84.93 cM
• Alliance: Trp53bp2^em8Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 deleted 3710 bp. (J:334232)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trp53bp2 Mutation: 52 strains or lines available

References

• Original: J:334232 Xie F, et al., Dysregulated hepatic lipid metabolism and gut microbiota associated with early-stage NAFLD in ASPP2-deficiency mice. Front Immunol. 2022;13:974872
• All: 1 reference(s)