Sctr^tm2Bkcc
Targeted Allele Detail

Summary

• Symbol: Sctr^tm2Bkcc
• Name: secretin receptor; targeted mutation 2, Billy K C Chow
• MGI ID: MGI:7448468
• Synonyms: Sctr^fl
• Gene: Sctr Location: Chr1:119934710-119991269 bp, + strand Genetic Position: Chr1, 52.57 cM
• Alliance: Sctr^tm2Bkcc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:334238
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct created a floxed allele. (J:334238)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sctr Mutation: 27 strains or lines available

References

• Original: J:334238 Zhang F, et al., Secretin receptor deletion in the subfornical organ attenuates the activation of excitatory neurons under dehydration. Curr Biol. 2022 Nov 21;32(22):4832-4841.e5
• All: 2 reference(s)