Tg(Prl-cre)#Salr
Transgene Detail
|
Symbol: |
Tg(Prl-cre)#Salr |
Name: |
transgene insertion, Stephen A Liebhaber |
MGI ID: |
MGI:7448387 |
Synonyms: |
Prl-Cre |
Transgene: |
Tg(Prl-cre)#Salr Location: unknown
|
Alliance: |
Tg(Prl-cre)#Salr page
|
|
|
Transgene Type: |
|
Transgenic (Recombinase) |
Mutation: |
|
Insertion
|
|
|
Tg(Prl-cre)#Salr expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Prl (MGI:97762) |
|
|
|
|
Mutation details: A Cre sequence was inserted into the beginning of exon 2 of the Prl ORF in a BAC clone (RP23-441I3 BAC) containing the mouse Prl locus with more than 50 kb of upstream and downstream sequences. The PRL start codon was maintained in the Cre ORF such that the protein product was the first of approximately 10 amino acids of PRL, followed by the full Cre recombinase protein. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:295321)
|
|
|
Activity: |
Tissue activity of this recombinase allele
|
Driver:
|
Prl
(mouse)
|
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
Original: |
J:295321 Peel MT, et al., The Transcription Factor NR4A2 Plays an Essential Role in Driving Prolactin Expression in Female Pituitary Lactotropes. Endocrinology. 2020 May 1;161(5) |
All: |
1 reference(s) |
|