Perm1^em1Jswn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Perm1^em1Jswn
• Name: PPARGC1 and ESRR induced regulator, muscle 1; endonuclease-mediated mutation 1, Junco S Warren
• MGI ID: MGI:7447455
• Gene: Perm1 Location: Chr4:156300325-156305764 bp, + strand Genetic Position: Chr4, 88.62 cM
• Alliance: Perm1^em1Jswn page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 deleted 1,157 bp. (J:334191)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Perm1 Mutation: 52 strains or lines available

References

• Original: J:334191 Oka SI, et al., PERM1 regulates energy metabolism in the heart via ERRalpha/PGC-1alpha axis. Front Cardiovasc Med. 2022;9:1033457
• All: 1 reference(s)