Lyz1tm2.1(cre/ERT2)Cle
Targeted Allele Detail
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Symbol: |
Lyz1tm2.1(cre/ERT2)Cle |
Name: |
lysozyme 1; targeted mutation 2.1 Hans Clevers |
MGI ID: |
MGI:7447075 |
Synonyms: |
pLys-CreErt2 |
Gene: |
Lyz1 Location: Chr10:117123702-117128773 bp, - strand Genetic Position: Chr10, 65.35 cM
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Alliance: |
Lyz1tm2.1(cre/ERT2)Cle page
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Germline Transmission: |
Earliest citation of germline transmission:
J:285915
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Parent Cell Line: |
IB10/E14IB10 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Mutation: |
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Insertion
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Lyz1tm2.1(cre/ERT2)Cle expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Lyz1 (MGI:96902) |
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Mutation details: A Cre/ERT2 gene was inserted onto the ATG of the Lyz1 gene through homologous recombination in ES cells. The neomycin selection cassette was flanked by Frt recombination sites and excised in vivo by crossing the mice with the general FLP deleter strain.
(J:285915)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Lyz1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Lyz1 Mutation: |
14 strains or lines available
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Original: |
J:285915 van Es JH, et al., Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion. Proc Natl Acad Sci U S A. 2019 Dec 16; |
All: |
1 reference(s) |
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